1224690-84-9

  • Product Name:tianeptine sulfate
  • Molecular Formula:C42H56Cl2N4O14S3
  • Purity:99%
  • Molecular Weight:
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Product Details

1224690-84-9 On Sale, Tianeptine sulfate Wholesaler, low price

  • Molecular Formula:2(C21H25ClN2O4S).H2SO4.2(H2O)
  • Molecular Weight:1008.01344
  • PSA:291.62000 
  • LogP:11.75800 

Tianeptine sulfate 1224690-84-9 Usage

Tianeptine sodium is an antidepressant reported to act by increas-ing (rather than inhibiting) the presynaptic reuptake of serotonin. Tianeptine is an effective antidepressant with a previously unknown mechanism of action.

The sulfate salt of tianeptine can be used to provide pharmaceutical compositions for the treatment of conditions known in the art, such as one or more depressive disorders, irritable bowel syndrome (IBS), attention deficit hyperactivity disorder (ADHD), one or more neurodegenerative diseases, and asthma.

 

Tianeptine sulfate 1224690-84-9 Relevant articles

Opioid-like adverse effects of tianeptine in male rats and mice

T. R. Baird, H. I. Akbarali, W. L. Dewey, H. Elder, M. Kang, S. A. Marsh, M. R. Peace, J. L. Poklis, E. J. Santos & S. S. Negus

Psychopharmacology volume 239, pages2187–2199 (2022)

The present study evaluated tianeptine in a rat model of abuse potential assessment and in mouse models of motor, gastrointestinal, and respiratory adverse effects.

Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain

Hyung Gon Lee, Yeo Ok Kim, Jeong Il Choi, Xue Hao Han, Yang Un Shin, Myung Ha Yoon

Korean J Pain 2022;35(1):59-65.

Intrathecal pregabalin and tianeptine increased the mechanical withdrawal threshold in a dose-dependent manner, but intrathecal clopidogrel had little effect on the mechanical withdrawal threshold. An additive effect was noted between pregabalin and tianeptine, but not between pregabalin and clopidogrel.

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