141-90-2

  • Product Name:2-Thiouracil
  • Molecular Formula:C4H4N2OS
  • Purity:99%
  • Molecular Weight:
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Product Details

Appearance:white to cream fine crystalline powder

2-Thiouracil 141-90-2 manufacturer, in stock, low price

  • Molecular Formula:C4H4N2OS
  • Molecular Weight:128.155
  • Appearance/Colour:white to cream fine crystalline powder 
  • Vapor Pressure:5.45E-05mmHg at 25°C 
  • Melting Point:>300 °C(lit.) 
  • Refractive Index:1.677 
  • Boiling Point:337.2 °C at 760 mmHg 
  • PKA:pKa 7.46 (Uncertain) 
  • Flash Point:157.7 °C 
  • PSA:80.74000 
  • Density:1.46 g/cm3 
  • LogP:0.43250 

2-Thiouracil 141-90-2 Usage

2-Thiouracil is a chemical derivative of uracil in which the oxygen atom in the 2-position of the ring is substituted by sulfur. It is white to cream fine crystalline powder. It acts as an anticancer, antithyroid, and antiviral agent. 

 

Definition

ChEBI: A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.

Purification Methods

Crystallise 2-thiouracil from water or EtOH. 

InChI:InChI=1/C4H4N2OS/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)

 

Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world,  The predecessor of Shanghai Upbio Tech Co.,Ltd was Onchem (China) Co.,Ltd in 2010,Specialized in APIs, chemical intermediates, herbal extract and pharmaceutical raw materials.

We have our own GMP factory with R&D centure.and cleaning workshop , and some main products produced by our own lab and R&D centure.besides we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse. 

141-90-2 Relevant articles

A simple strategy to enhance the luminescence of metal nanoclusters and its application for turn-on detection of 2-thiouracil and hyaluronidase

Miao Liang , Zhongli Lei , Yiling Li, Yan Xiao

Talanta Volume 236, 1 January 2022, 122876

Since 2-thiouracil (2-TU), a common anticancer, antithyroid, and antiviral agent, featured a similar molecular structure of ATT, this luminescence enhancement strategy can be designed to sensitive and selective turn-on detect 2-TU.

Kinetics and adsorption isotherm model of 2-thiouracil adsorbed onto the surface of reduced graphene oxide-copper oxide nanocomposite material

Pramanand Kumar, Subrata Das

Journal of Molecular Structure Volume 1268, 15 November 2022, 133723

Thiouracil is a nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group. It has a role as an antithyroid drug and a metabolite. We report the synthesis of rGO-CuO using the chemical modification method, characterization, and the adsorption isotherm behavior of the nanocomposite material for the removal of 6-amino-2-thiouracil (6A2TU) and 6-amino-5-nitroso-2-thiouracil (6A5NTU) in an aqueous medium.

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