Product Details
Appearance:white to cream fine crystalline powder
2-Thiouracil 141-90-2 manufacturer, in stock, low price
- Molecular Formula:C4H4N2OS
- Molecular Weight:128.155
- Appearance/Colour:white to cream fine crystalline powder
- Vapor Pressure:5.45E-05mmHg at 25°C
- Melting Point:>300 °C(lit.)
- Refractive Index:1.677
- Boiling Point:337.2 °C at 760 mmHg
- PKA:pKa 7.46 (Uncertain)
- Flash Point:157.7 °C
- PSA：80.74000
- Density:1.46 g/cm3
- LogP:0.43250
2-Thiouracil 141-90-2 Usage
2-Thiouracil is white to cream fine crystalline powder. It acts as an anticancer, antithyroid, and antiviral agent. 2-Thiouracil is a substance with effective biological and pharmacological activities, which has been used in the synthesis and characterization of silver colloid and film substrates and their applications in surface-enhanced Raman scattering (SERS).
Definition
ChEBI: A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.
Purification Methods
Crystallise 2-thiouracil from water or EtOH.
InChI:InChI=1/C4H4N2OS/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
141-90-2 Relevant articles
A simple strategy to enhance the luminescence of metal nanoclusters and its application for turn-on detection of 2-thiouracil and hyaluronidase
Miao Liang , Zhongli Lei , Yiling Li, Yan Xiao
Talanta Volume 236, 1 January 2022, 122876
Since 2-thiouracil (2-TU), a common anticancer, antithyroid, and antiviral agent, featured a similar molecular structure of ATT, this luminescence enhancement strategy can be designed to sensitive and selective turn-on detect 2-TU.
Kinetics and adsorption isotherm model of 2-thiouracil adsorbed onto the surface of reduced graphene oxide-copper oxide nanocomposite material
Pramanand Kumar, Subrata Das
Journal of Molecular Structure Volume 1268, 15 November 2022, 133723
We report the synthesis of rGO-CuO using the chemical modification method, characterization, and the adsorption isotherm behavior of the nanocomposite material for the removal of 6-amino-2-thiouracil (6A2TU) and 6-amino-5-nitroso-2-thiouracil (6A5NTU) in an aqueous medium.
141-90-2 Process route
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- 75039-91-7
ethyl 3-(N-methylcyanamino)-2-butenoate
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- 141-90-2,156-82-1
2-thiouracil
-
- 598-52-7
1-(methyl)-thiourea
-
- 33238-58-3
1,6-dimethyl-2-thiouracil
| Conditions | Yield |
|---|---|
|
With hydrogen sulfide; In ethanol; at 30 - 40 ℃;
|
0.2 g 0.2 g 0.5 g |
-
- 13233-20-0,13239-97-9
2-thiocytidine
-
- 141-90-2,156-82-1
2-thiouracil
-
- 333-49-3
2-thiocytosine
-
- 20235-78-3
2-thiouridine
| Conditions | Yield |
|---|---|
|
With formic acid; water; at 60 ℃; for 1296h; pH=3;
|
38% 34% 18% |
141-90-2 Upstream products
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6965-19-1
2-ethylthio-3H-pyrimidin-4-one
-
98484-57-2
(3t-ethoxy-acryloyl)-thiourea
-
10601-80-6
ethyl 3,3-diethoxypropanoate
-
17356-08-0
thiourea
141-90-2 Downstream products
-
21052-18-6
2-thio-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-(3H)pyrimidine-2,4-dione
-
5751-20-2
2-Methylthiouracil
-
6327-98-6
2-methylthio-3-methylpyrimidin-4(3H)-one
-
6330-98-9
1-methyl-2-methysulfanylpyrimidin-4(1H)-one
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