Product Details
Appearance:White crystalline powder
Hot Sale, D-Mannitol 69-65-8 Good Supplier In China with reasonable price
- Molecular Formula:C6H14O6
- Molecular Weight:182.174
- Appearance/Colour:White crystalline powder
- Vapor Pressure:7.22E-12mmHg at 25°C
- Melting Point:167-170 °C(lit.)
- Refractive Index:1.597
- Boiling Point:494.865 °C at 760 mmHg
- PKA:13.5(at 18℃)
- Flash Point:292.497 °C
- PSA：121.38000
- Density:1.596 g/cm3
- LogP:-3.58540
D-Mannitol 69-65-8 Usage
D-mannitol is the D enantiomer of mannitol.
D-Mannitol, a naturally occurring six-carbon sugar alcohol or polyol, is found in plants such as algae, onions, grasses, and olives. It used to increase urine production (diuretic). It is also used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). The acyclic sugar alcohol D-mannitol is an excipient commonly used in the pharmaceutical formulation of tablets or granulated powders for oral use. It's chief advantage is good chemical stability.
Definition
ChEBI: The D-enantiomer of mannitol.
Brand name
Osmitrol (Baxter Healthcare); Resectisol (B Braun).
Therapeutic Function
Diuretic, Diagnostic aid (kidney function)
General Description
Odorless white crystalline powder or free-flowing granules. Sweet taste.
Air & Water Reactions
Water soluble.
Hazard
Mildly toxic; mutagen.
Fire Hazard
D-Mannitol is probably combustible.
InChI:InChI=1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6+/m0/s1
69-65-8 Relevant articles
A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells
David Pérez , María Luisa Moyá , María Bautista , Rosa León , Ana Molina-Márquez , Marta Vila , Lucía Romero-Azogil , Elena Benito , María de Gracia García-Martín , Paula Moreno-Gordillo , Iván V. Rosado , Fernando R. Balestra , Pablo Huertas , Manuel López-López , Pilar López-Cornejo
Colloids and Surfaces B: Biointerfaces Volume 224, April 2023, 113219
In the present work, a sugar-based cationic polyurethane derived from D-mannitol, PUMan, has been synthesized to be used as a nanocarrier of genetic material.
d-Mannitol based surfactants for cosmetic and food applications and hydrogels to produce stabilized Ag nanoparticles
SK Singh, S Dey, MP Schneider, S Nandi
New J. Chem., 2022,46, 6193-6200
A series of mannitol based amphiphiles were synthesized based mainly on renewable resources. All these amphiphiles are surfactants with excellent foaming abilities and low CMC values.
Elucidating the effect of solid base on the hydrogenation of C5 and C6 sugars over Pt–Sn bimetallic catalyst at room temperature
Tathod, Anup P.,Dhepe, Paresh L.
, (2021/05/19)
Conversion of sugars into sugar alcohols at room temperature with exceedingly high yields are achieved over Pt–Sn/γ-Al2O3 catalyst in the presence of calcined hydrotalcite. In the current work, effect of both; solid base and Sn as a promoter has been studied to improve the yields of sugar alcohols from various C5 and C6 sugars at very mild reaction conditions.
69-65-8 Process route
-
- 141-46-8
Glycolaldehyde
-
- 2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6
1,2,3,4-butanetetrol
-
- 50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4
sorbitol
| Conditions | Yield |
|---|---|
|
Glycolaldehyde; With L-proline; In water; at 20 ℃;
With sodium tetrahydroborate; In methanol; at 0 ℃; Title compound not separated from byproducts;
|
-
cellulose
- 9004-34-6
cellulose
-
- 57-55-6,63625-56-9
propylene glycol
-
- 2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6
1,2,3,4-butanetetrol
-
- 107-21-1
ethylene glycol
-
- 50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4
sorbitol
| Conditions | Yield |
|---|---|
|
With hydrogen; In water; at 199.84 ℃; for 0.5h; under 45004.5 Torr; Autoclave;
|
69-65-8 Upstream products
-
57-48-7
D-Fructose
-
58-86-6
D-xylose
-
3458-28-4
D-Mannose
-
64-17-5
ethanol
69-65-8 Downstream products
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7208-47-1
hexaacetyl-D-mannitol
-
147235-76-5
hexakis-O-(2-carboxy-benzoyl)-D-mannitol
-
10300-97-7
1,3;4,6-di-O-methylene-D-mannitol
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5434-31-1
1,3-2,5-4,6-tri-O-methylene-D-mannitol
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