Product Details
Appearance:white crystalline powder
Best quality Adenosine 58-61-7 supplier, good producer
- Molecular Formula:C10H13N5O4
- Molecular Weight:267.244
- Appearance/Colour:white crystalline powder
- Vapor Pressure:3.26E-19mmHg at 25°C
- Melting Point:234-236 °C(lit.)
- Refractive Index:1.907
- Boiling Point:676.3 °C at 760 mmHg
- PKA:3.6, 12.4(at 25℃)
- Flash Point:362.8 °C
- PSA：139.54000
- Density:2.08 g/cm3
- LogP:-1.39880
Adenosine 58-61-7 Usage
Adenosine is an important nucleoside composed of adenine and ribose. White, crystalline, odorless powder, mild, saline, or bitter taste, quite soluble in hot water, practically insoluble in alcohol. Studies indicate anti-wrinkle and skinsmoothing capacities. Adenosine is one of the important active components in the body, helps in cellular energy transfer by forming molecules like adenosine triphosphate (ATP) and adenosine diphosphate (ADP). The concentration of adenosine can be increased by endogenous or exogenous pathways due to its short half-life and high inactivation properties so it is currently widely used in the treatment of diseases of the central nervous system (CNS) and the cardiovascular systems, and the mechanisms are related to the disease types, disease locations, and the adenosine receptors distribution in the CNS.
Brand name
Adenocard (Astellas); Adenoscan (Astellas).
InChI:InChI=1/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6+,7+,10+/m1/s1
58-61-7 Relevant articles
Adenosine and the cardiovascular system
Allison B. Reiss, David Grossfeld, Lora J. Kasselman, Heather A. Renna, Nicholas A. Vernice, Wendy Drewes, Justin Konig, Steven E. Carsons & Joshua DeLeon
American Journal of Cardiovascular Drugs volume 19, pages449–464 (2019)
Adenosine is an endogenous nucleoside with a short half-life that regulates many physiological functions involving the heart and cardiovascular system. We highlight future directions of research in the application of adenosine as an approach to improving outcomes in persons with cardiovascular disease.
Adenosine, caffeine, and sleep–wake regulation: state of the science and perspectives
Carolin Franziska Reichert, Tom Deboer, Hans-Peter Landolt
Journal of Sleep Research August 2022 e13597
Whether adenosine is also involved in the regulation of the normal occurrence of the daily sleep–wake cycle is less certain and needs further investigation. The currently available data do not suggest the expected time course of daily changes in adenosine that would parallel the daily changes in NREM sleep EEG SWA, which is widely accepted as a physiological marker of sleep homeostasis.
58-61-7 Process route
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- 917-44-2
Adenosyl-<3'-5'>-adenosyl-<3'-5'>-adenosin
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- 61-19-8,24937-83-5,67583-85-1
5'-adenosine monophosphate
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- 58-61-7
adenosine
| Conditions | Yield |
|---|---|
|
With ribonuclease T2; In water; at 37 ℃; for 1h; Enzymatic reaction;
|
-
- 2391-46-0,30066-84-3,88054-63-1
adenyl(3'-5')phophoadenine
-
- 61-19-8,24937-83-5,67583-85-1
5'-adenosine monophosphate
-
- 58-61-7
adenosine
| Conditions | Yield |
|---|---|
|
With 1,8-bis(1-hexyloxy-1-azonia-4,7-diazatricyclo[5.2.1.0(4,10)]decane)anthracene-9,10-dione dibromide; water; at 37 ℃; for 16h;
|
58-61-7 Upstream products
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2004-06-0
6-Chloropurine riboside
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342-69-8
6-methylmercaptopurine riboside
-
84-21-9
adenosine monophosphate
-
61-19-8
5'-adenosine monophosphate
58-61-7 Downstream products
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2382-66-3
Cytidin-(3',5')-adenosin
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2140-79-6
2'-O-methyl adenosine
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18048-85-6
5'-O-(triphenylmethyl)adenosine
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31085-55-9
(2R,3R,4S,5R)-2-(6-(tritylamino)-9H-purin-9-yl)-5-((trityloxy)methyl)tetrahydrofuran-3,4-diol
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