Product Details
Appearance:white to slightly yellow crystalline powder
Metronidazole 443-48-1 trader for sale with best price
- Molecular Formula:C6H9N3O3
- Molecular Weight:171.156
- Appearance/Colour:white to slightly yellow crystalline powder
- Vapor Pressure:2.67E-07mmHg at 25°C
- Melting Point:159-161 °C(lit.)
- Refractive Index:1.612
- Boiling Point:405.4 °C at 760 mmHg
- PKA:pKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)
- Flash Point:199 °C
- PSA：83.87000
- Density:1.45 g/cm3
- LogP:0.61520
Metronidazole 443-48-1 Usage
Metronidazole is a nitroimidazole antibiotic, also known as metronidazol and novonidazol. It was initially used to treat vaginal trichomaniasis, with very significant clinical effects. Metronidazole, an antibiotic against broad anaerobes, was linked to fluorouridine to form an amphiphilic small molecule, metronidazole–fluorouridine, which further autoassembled as metronidazole–fluorouridine nanoparticles (MTI-FDU) in a hydrophilic solution. It was demonstrated that metronidazole could induce maternal and fetal hepatotoxicity. Metronidazole (MNZ) is commonly used to treat diseases associated with parasites, microaerophilic bacteria, and anaerobic bacteria. It is also added to poultry and fish feed to help eliminate parasites .
Brand name
Flagyl (Searle); Metrogel (Galderma); Metrogel (3M Pharmaceuticals); Noritate(Sanofi Aventis); Vandazole (Teva).
Shipping
UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
InChI:InChI=1/C6H9N3O3/c1-5-7-6(9(11)12)4-8(5)2-3-10/h4,10H,2-3H2,1H3
443-48-1 Relevant articles
Promoted elimination of metronidazole in ferrous ions activated peroxydisulfate process by gallic acid complexation
Shoufeng Tang, Eryu Zhu, Zhihui Zhai, Huilin Liu, Zhibing Wang, Tifeng Jiao, Qingrui Zhang, Deling Yuan
Chemosphere Volume 319, April 2023, 138025
As an antimicrobial and antigenic agent, metronidazole (MTZ) has been broadly used in prevention and infection management resulted from anaerobic bacteria (Rodríguez-Chueca et al., 2019). In this work, the environmentally friendly GA was added into the PDS/Fe2+ Fenton-like system as a complexing agent for MTZ removal.
Reduction of metronidazole in municipal wastewater and protection of activated sludge system using a novel immobilized Aspergillus tabacinus LZ-M
Xuan Yu , Chunlan Mao , Wenxue Wang , Saurabh Kulshrestha , Peng Zhang , Muhammad Usman , Simin Zong , Mian Gul Hilal , Yitian Fang , Huawen Han , Xiangkai Li
Bioresource Technology Volume 369, February 2023, 128509
Immobilized LZ-M was introduced into AAS systems for bioaugmentation, effectively removing Metronidazole (MNZ) from wastewater and increasing COD degradation efficiency and gas production. Furthermore, bioaugmentation reduced the toxic effect of MNZ on activated sludge, facilitated its metabolism and growth, and maintained microbial community stability.
Synthetic method for producing metronidazole raw medicinal material
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Paragraph 0013-0014, (2018/07/30)
The invention discloses a synthetic method for producing a metronidazole raw medicinal material. The method disclosed by the invention is mild in preparation condition and low in cost, and is applicable for industrial production.
443-48-1 Process route
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- 13182-85-9
metronidazole palmitate
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- 57-10-3
1-hexadecylcarboxylic acid
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- 443-48-1
metronidazole
| Conditions | Yield |
|---|---|
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With hydrogenchloride; citrate-phosphate-borate buffer; In ethanol; at 60 ℃; pH=3; Further Variations:; pH-values; Kinetics;
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leucine ester of metronidaxole hydrochloride
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- 61-90-5,21675-61-6,25248-98-0,70-45-1
L-leucine
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- 443-48-1
metronidazole
| Conditions | Yield |
|---|---|
|
With sodium chloride; at 25 ℃; Rate constant; rate constant of hydrolysis; pH 4.5; other pH, buffers;
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With water; at 37 ℃; Rate constant; rate constant of hydrolysis;
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443-48-1 Upstream products
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75-21-8
oxirane
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696-23-1
2-methyl-5-nitro-1H-imidazole
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73334-05-1
metronidazole phosphate
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89218-56-4
glycine ester of metronidaxole
443-48-1 Downstream products
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30529-13-6
2-(4-[1,3]dioxolan-2-yl-styryl)-5-nitro-1-vinyl-1H-imidazole
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13182-87-1
4-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethoxy]-4-oxobutanoic acid
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104575-36-2
3,4,5-trimethoxy-benzoic acid 2-(2-methyl-5-nitro-imidazol-1-yl)-ethyl ester
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36698-08-5
1-(2-Benzoyloxyethyl)-5-nitro-2-imidazole-α-phenylethenol benzoate
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