• Product Name:Dapoxetine hydrochloride
  • Molecular Formula:C21H24ClNO
  • Purity:99%
  • Molecular Weight:

Product Details

Appearance:off-white cryst

Dapoxetine hydrochloride 129938-20-1 supplier, 129938-20-1 manufacturer with low price

  • Molecular Formula:C21H24ClNO
  • Molecular Weight:341.8744
  • Appearance/Colour:off-white cryst 
  • Vapor Pressure:1.27E-09mmHg at 25°C 
  • Melting Point:175-179 °C 
  • Boiling Point:454.4 °C at 760 mmHg 
  • Flash Point:132.6 °C 
  • PSA:12.47000 
  • LogP:5.71360 

Dapoxetine hydrochloride 129938-20-1 Usage

Dapoxetine HCl (DH), a selective serotonin reuptake inhibitor, belonging to the class of SSRIs, is a white to slightly yellow powder. It is freely soluble in methanol, propylene glycol, some organic solvents (eg. N,N-dimethylformamide) , slightly soluble in ethanol and almost insoluble in water. It is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Dapoxetine hydrochloride (DPX) has a low oral bioavailability due to significant hepatic first pass metabolism. In addition, DPX is a weakly basic drug with a pH dependent solubility that could limit its dissolution in the body neutral fluids.

Brand name


General Description

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.

Biochem/physiol Actions

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation


Dapoxetine hydrochloride 129938-20-1 Relevant articles

Tuning fluorescence of dapoxetine by blocking of photoinduced electron transfer (PET): Application in real human plasma

Mohamed Ahmed Elsayed, Khaled Abdel-Hakam Abbas, Hani Shaaban Abdelmontaleb, Abobakr A. Mohamed

Early View, 14 March 2023

Photoinduced electron transfer (PET) is the most common mechanism proposed to account for quenching of fluorophores. Herein, the intrinsic fluorescence of dapoxetine (DPX) hydrochloride is in the “OFF” state, owing to the deactivation effect of PET.

Effect of Dapoxetine Hydrochloride on Sperm Quality and Psychological Stress in Patients with Premature Ejaculation

Jia-jia DENG

Chinese health care

Sertraline hydrochloride and dapoxetine hydrochloride can improve sperm quality in patients with premature ejaculation, but dapoxetine hydrochloride can alleviate psychological stress and improve ejaculation control ability, which is helpful to improve sexual life quality of patients.